What is that sequence called?
(a) CAAT box
(b) GGTT box
(c) AAAT box
(d) TATA box
[CBSE AIPMT 2005]
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CONNECTING MINDS
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During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point.
During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point.
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Correct Option (d) Reason : TATA box is present in eukaryotic promoter region. It has a resemblance with Pribnow box of prokaryotes. TATA box was identified by Dr. Hogness and so, it is also called as Hogness box. It is a 7 bp long region located 20 bp upstream to the start point.
During the process of transcription the RNA polymerase (a holoenzyme which has a core unit and a sigma factor for proper initiation of transcription) binds to TATA box due to which DNA assumes a saddle like structure at this place.