(a) reduction in X-complement
(b) increase in X-complement
(c) moderate increase in Y-complement
(d) large increase in Y-complement
[CBSE AIPMT 1998]
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Mental retardation in man, associated with sex chromosomal abnormality is usually due to
Mental retardation in man, associated with sex chromosomal abnormality is usually due to
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Correct Option (b) Reason : Sterile males with undeveloped testes, mental retardation, etc. are due to increase in their X-complement which takes place in a disorder called. Klinefelter's syndrome. These are formed by union of an XX egg and a normal Y sperm or normal X egg and abnormal XY sperm. The individual thus has 47 chromosomes (44 + XXY).